Invention Grant
- Patent Title: PRMT5 inhibitors
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Application No.: US16762201Application Date: 2018-11-05
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Publication No.: US10947234B2Publication Date: 2021-03-16
- Inventor: Michelle R. Machacek , David J. Witter , Michael Hale Reutershan , Michael D. Altman , Paul Anthony Stupple
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sarah L. Hooson; Catherine D. Fitch
- International Application: PCT/US2018/059130 WO 20181105
- International Announcement: WO2019/094311 WO 20190516
- Main IPC: C07D471/04
- IPC: C07D471/04

Abstract:
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts thereof, which are PRMT5 inhibitors.
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