- 专利标题: Heterocyclic compound used as FGFR inhibitor
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申请号: US16068791申请日: 2017-01-09
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公开(公告)号: US10934311B2公开(公告)日: 2021-03-02
- 发明人: Hancheng Zhang , Shifeng Liu
- 申请人: Hangzhou Innogate Pharma Co., Ltd.
- 申请人地址: CN Zhejiang
- 专利权人: Hangzhou Innogate Pharma Co., Ltd.
- 当前专利权人: Hangzhou Innogate Pharma Co., Ltd.
- 当前专利权人地址: CN Zhejiang
- 代理机构: Ice Miller LLP
- 优先权: CN201610015536.X 20160108
- 国际申请: PCT/CN2017/070674 WO 20170109
- 国际公布: WO2017/118438 WO 20170713
- 主分类号: C07D498/04
- IPC分类号: C07D498/04 ; C07D413/12 ; C07D471/08 ; A61P35/00
摘要:
A heterocyclic compound is described, which is an inhibitor of FGFR (fibroblast growth factor receptor). Specifically, it is a compound represented by the following formula (I), including an isomer (enantiomer or diastereomer) which may be present, or a pharmaceutically acceptable salt thereof, prodrugs, deuterated derivatives, hydrates, solvates. The definition of each group in the formula (I) is as described in the specification. The compound of the present invention has FGFR inhibitory activity and can be used for preventing or treating a disease associated with FGFR activity or expression.
公开/授权文献
- US20190100531A1 HETEROCYCLIC COMPOUND USED AS FGFR INHIBITOR 公开/授权日:2019-04-04
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