- 专利标题： 4-imidazopyridazin-1-yl-benzamides as Btk inhibitors
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申请号： US16276161申请日： 2019-02-14
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公开(公告)号： US10934296B2公开(公告)日： 2021-03-02
- 发明人: Tjeerd A. Barf , Christiaan Gerardus Johannes Maria Jans , Adrianus Petrus Antonius de Man , Arthur A. Oubrie , Hans C. A. Raaijmakers , Johannes Bernardus Maria Rewinkel , Jan Gerard Sterrenburg , Jacobus C. H. M. Wijkmans
- 申请人： Merck Sharp & Dohme B.V.
- 申请人地址： NL Haarlem
- 专利权人： Merck Sharp & Dohme B.V.
- 当前专利权人： Merck Sharp & Dohme B.V.
- 当前专利权人地址： NL Haarlem
- 代理机构： Covington & Burling LLP
- 代理商 Melody Wu; Jennifer L. Robbins
- 优先权： EP11174578 20110719
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D519/00 ; A61K31/4985 ; A61K31/501 ; A61K31/506 ; A61K31/55 ; A61K31/5377
摘要：
The present invention relates to 6-5 membered fused pyridine ring compounds according to Formula (I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to Formula (I) in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
公开/授权文献
- US20190276456A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS 公开/授权日：2019-09-12
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