- 专利标题: Use of marizomib for the treatment of central nervous system (CNS) cancers
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申请号: US15611614申请日: 2017-06-01
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公开(公告)号: US10894036B2公开(公告)日: 2021-01-19
- 发明人: Mohit Trikha , Ann MacLaren , Nancy Levin
- 申请人: Celgene International II Sàrl
- 申请人地址: CH Couvet
- 专利权人: Celgene International II Sàrl
- 当前专利权人: Celgene International II Sàrl
- 当前专利权人地址: CH Couvet
- 代理机构: Cooley LLP
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/407 ; A61K39/395 ; C07K16/22 ; C07K16/28 ; A61N5/10 ; A61K39/00
摘要:
The present disclosure relates to treatment of central nervous system (CNS) cancers (e.g., malignant glioma, glioblastoma, or CNS-multiple myeloma) using marizomib. The disclosure further relates to uses of synergistic combinations of marizomib with additional therapeutic agents such as bevacizumab, daratumumab, temozolomide, pomalidomide, and radiotherapy.
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