- 专利标题: Methods for characterizing alternatively or aberrantly spliced mRNA isoforms
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申请号: US15315879申请日: 2015-06-10
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公开(公告)号: US10724092B2公开(公告)日: 2020-07-28
- 发明人: Atze Jacobus Bergsma , Erik van der Wal , Wilhelmus Wenceslaus Matthias Pijnappel , Antje Tjitske van der Ploeg , Arnoldus Reuser
- 申请人: Erasmus University Medical Center Rotterdam
- 申请人地址: NL Rotterdam
- 专利权人: Erasmus University Medical Center Rotterdam
- 当前专利权人: Erasmus University Medical Center Rotterdam
- 当前专利权人地址: NL Rotterdam
- 代理机构: Dentons US LLP
- 优先权: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@448a8985 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@241cc462
- 国际申请: PCT/NL2015/050420 WO 20150610
- 国际公布: WO2015/190921 WO 20151217
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12Q1/6876 ; C12Q1/6883 ; C12Q1/6844 ; C12Q1/6851 ; C12N15/11 ; C12N15/113
摘要:
The disclosure provides method and kits for characterizing spliced m RNA isoforms. The disclosure also provides methods of screening for mutations and oligonucleotides that modulate splicing.
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