The present disclosure relates to systems and methods for updating multiple value data structures using a single electronic activity. Exemplary embodiments may include hardware processors configured by machine-readable instructions to access electronic activities transmitted or received via electronic accounts associated with data source providers; to maintain and update node profiles; to determine a first activity field-value pair and a second activity field-value pair associated with a participant of the first electronic activity; to identify a first node profile of the node profiles that includes a first node field-value pair that matches the first activity field-value pair; to update a first value data structure corresponding to a first value included in the first node field-value pair by adding a first entry to the first value data structure identifying the first electronic activity; and to update a second value data structure corresponding to a second value.