A clamp for retaining an IV tube having a pair of clamp sections configured to be selectively secured together. Each clamp section includes a semi-cylindrical surface, and the semi-cylindrical surfaces are positioned to mirror one another when the clamp sections are secured together to frictionally engage around the IV tube. Each clamp section has a finger grip on an outer surface which is positioned on an opposite side of the clamp section from the semi-cylindrical surface. Each finger grip also has an arched surface which includes a medial portion positioned between each end of the finger grips, and at least one end of the finger grip flares away from the semi-cylindrical surface. The finger grip can have a finger shield which extends laterally beyond the semi-cylindrical surface. At least one of the finger grips may be symmetrical.