- 专利标题： Methods for producing enteroendocrine cells that make and secrete insulin
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申请号： US15241674申请日： 2016-08-19
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公开(公告)号： US10544415B2公开(公告)日： 2020-01-28
- 发明人: Chutima Talchai , Domenico Accili
- 申请人： The Trustees Of Columbia University In The City Of New York
- 申请人地址： US NY New York
- 专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人地址： US NY New York
- 代理机构： Beusse Wolter Sanks & Maire
- 代理商 Timothy H. Van Dyke
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; G01N33/50 ; A61K31/7088 ; A61K39/395 ; C12N5/071
摘要：
Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more forkhead box O (Foxo) proteins or biologically active fragments or variants thereof.
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