- 专利标题： 5-hydroxytryptamine receptor 7 activity modulators and their method of use
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申请号： US15510152申请日： 2015-09-10
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公开(公告)号： US10544117B2公开(公告)日： 2020-01-28
- 发明人: Daniel J. Canney , Benjamin E. Blass , Rong Gao , Magid Abou-Gharbia
- 申请人： Temple University—Of the Commonwealth System of Higher Education
- 申请人地址： US PA Philadelphia
- 专利权人： Temple University—Of The Commonwealth System of Higher Education
- 当前专利权人： Temple University—Of The Commonwealth System of Higher Education
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Proskauer Rose LLP
- 代理商 Fangli Chen
- 国际申请： PCT/US2015/049303 WO 20150910
- 国际公布： WO2016/040554 WO 20160317
- 主分类号： C07D405/12
- IPC分类号： C07D405/12 ; A61K31/496 ; C07D307/33 ; C07D307/94 ; C07D405/06
摘要：
Pharmaceutical compositions of the invention comprise functionalized lactone derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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