- 专利标题： D3 dopamine receptor agonists to treat dyskinesia in Parkinson's disease
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申请号： US15497287申请日： 2017-04-26
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公开(公告)号： US10543180B2公开(公告)日： 2020-01-28
- 发明人: Sandhya Kortagere , Eldo V. Kuzhikandahil
- 申请人： DREXEL UNIVERSITY , RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- 申请人地址： US PA Philadelphia US NJ New Brunswick
- 专利权人： Drexel University,Rutgers, The State University of New Jersey
- 当前专利权人： Drexel University,Rutgers, The State University of New Jersey
- 当前专利权人地址： US PA Philadelphia US NJ New Brunswick
- 代理机构： Saul Ewing Arnstein & Lehr LLP
- 代理商 Kathryn Doyle; Domingos J. Silva
- 主分类号： A61K31/137
- IPC分类号： A61K31/137 ; A61K45/06 ; A61K31/198 ; A61K31/4045 ; A61K31/428 ; A61K31/473 ; A61K31/48 ; A61K31/506 ; A61K31/519 ; A61K31/5513 ; A61K31/4184 ; C07C211/29 ; C07C215/08 ; C07C215/54 ; C07C217/62 ; C07D209/14 ; C07D235/16 ; C07D471/04
摘要：
The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.
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