发明授权
- 专利标题: Kojic acid polymers
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申请号: US15565313申请日: 2016-04-11
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公开(公告)号: US10543162B2公开(公告)日: 2020-01-28
- 发明人: Kathryn Uhrich , Kervin Smith , Jonathan Faig
- 申请人: Rutgers, The State University of New Jersey
- 申请人地址: US NJ New Brunswick
- 专利权人: Rutgers, The State University of New Jersey
- 当前专利权人: Rutgers, The State University of New Jersey
- 当前专利权人地址: US NJ New Brunswick
- 代理机构: Viksnins Harris Padys Malen LLP
- 国际申请: PCT/US2016/026931 WO 20160411
- 国际公布: WO2016/164898 WO 20161013
- 主分类号: A61K8/85
- IPC分类号: A61K8/85 ; A61K31/351 ; A61K47/59 ; A61K8/49 ; A61K9/00 ; A61P17/00 ; A61Q19/02 ; C08G64/06
摘要:
A controlled release system for kojic acid having improved stability has been identified. To minimize degradation, kojic acid was incorporated into a hydrolytically degradable polymer (e.g., a polycarbonate-ester)). By synthesizing polymer precursors containing kojic acid-linker-kojic acid chemical structures, versatile monomers were developed that can be used to modulate polymer properties. Additionally the synthetic method lends itself to the development of other polymer systems. Polymers having one or more groups that will yield kojic acid upon degradation of the polymer backbone, as well as methods of use thereof are described.
公开/授权文献
- US20180116945A1 Kojic Acid Polymers 公开/授权日:2018-05-03
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