- 专利标题： Seneca valley virus (SVV) cellular receptor targeted oncotherapy
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申请号： US15780898申请日： 2016-12-02
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公开(公告)号： US10537599B2公开(公告)日： 2020-01-21
- 发明人: Linde Miles , John Poirier , Charles Rudin
- 申请人： Memorial Sloan-Kettering Cancer Center
- 申请人地址： US NY New York
- 专利权人： Memorial Sloan-Kettering Cancer Center
- 当前专利权人： Memorial Sloan-Kettering Cancer Center
- 当前专利权人地址： US NY New York
- 代理机构： Hunton Andrews Kurth LLP
- 国际申请： PCT/US2016/064679 WO 20161202
- 国际公布： WO2017/096201 WO 20170608
- 主分类号： A61K35/768
- IPC分类号： A61K35/768 ; G01N33/574 ; C12Q1/6886 ; A61P35/00 ; A61K45/06
摘要：
A method for selecting cancer patient for treatment with Seneca Valley Virus (SVV) by determining expression of ANTXR1 in a cancerous tissue in a cancer patient; and designating the cancer patient as a candidate for treatment with SVV if normal levels or elevated levels of ANTXR1 expression is detected in the cancerous tissue. Also a method for treating a cancer patient with SVV is disclosed.
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