- 专利标题： Use of 3-deoxyanthocyanidins for treating occular diseases
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申请号： US15577173申请日： 2016-05-27
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公开(公告)号： US10513503B2公开(公告)日： 2019-12-24
- 发明人: Valerie Fontaine , Rene Lafont , Jose-Alain Sahel , Stanislas Veillet
- 申请人： BIOPHYTIS , UNIVERSITE PIERRE ET MARIE CURIE—PARIS 6 (UPMC) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- 申请人地址： FR Paris FR Paris FR Paris FR Paris
- 专利权人： BIOPHYTIS,SORBONNE UNIVERSITE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
- 当前专利权人： BIOPHYTIS,SORBONNE UNIVERSITE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
- 当前专利权人地址： FR Paris FR Paris FR Paris FR Paris
- 代理机构： Young & Thompson
- 优先权： FR1554761 20150527
- 国际申请： PCT/FR2016/051262 WO 20160527
- 国际公布： WO2016/189260 WO 20161201
- 主分类号： C07D311/60
- IPC分类号： C07D311/60 ; A61K31/352
摘要：
Disclosed is a method for the treatment, prevention and/or stabilisation of ARMD, Stargardt disease, pigmentary retinopathy and/or diabetic retinopathy, including the application of a 3-deoxyanthocyanidin of formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and X− are as defined, with the condition that at least one of R1, R2, R3, R4 or R5 is a hydroxyl and at least one of R8, R9, R10 or R11 is a hydroxyl.
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