Systems, methods, and computer program products for coordinating operation of relevant systems after a passenger itinerary disruption. Responsive to a transfer request being received that includes at least a portion of a new travel itinerary to replace a disrupted travel itinerary of each of multiple passengers, an inventory system automatically updates counters based on the disrupted travel itinerary of each passenger and the new travel itinerary, and a reservation system automatically updates one or more reservation records to reflect an association between each passenger and the new travel itinerary. Thereafter, a ticketing system automatically performs a ticketing process for each passenger relative to the new travel itinerary, and a departure control system automatically transfers passenger data stored for each passenger in association with the disrupted travel itinerary of the passenger to a record associated with the new travel itinerary.