发明授权
- 专利标题： Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors
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申请号： US16179099申请日： 2018-11-02
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公开(公告)号： US10508098B2公开(公告)日： 2019-12-17
- 发明人: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , David R. Lancia, Jr.
- 申请人： FORMA Therapeutics, Inc.
- 申请人地址： US MA Watertown
- 专利权人： FORMA Therapeutics, Inc.
- 当前专利权人： FORMA Therapeutics, Inc.
- 当前专利权人地址： US MA Watertown
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 John P. Rearick; Nicholas J. Pace
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; C07D487/04 ; C07D471/04 ; C07D239/88
摘要：
The present disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R4′, X1, Y1, Y2, Y3, Y4, n, and m are described herein.
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