Invention Grant
- Patent Title: Enhanced expression and stability regions
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Application No.: US15916349Application Date: 2018-03-09
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Publication No.: US10415055B2Publication Date: 2019-09-17
- Inventor: Gang Chen , Robert Babb , James P. Fandl
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: US NY Tarrytown
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent Kristan Lansbery
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N15/86 ; C07K16/00 ; C12P21/02
Abstract:
Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Enhanced expression and stability regions (EESYRs) are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
Public/Granted literature
- US20180327777A1 ENHANCED EXPRESSION AND STABILITY REGIONS Public/Granted day:2018-11-15
Information query
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