- 专利标题： Carbonate prodrugs and methods of using the same
-
申请号： US15592048申请日： 2017-05-10
-
公开(公告)号： US10377779B2公开(公告)日： 2019-08-13
- 发明人: Naweed Muhammad , Keith R. Bley
- 申请人： Acorda Therapeutics, Inc.
- 申请人地址： US NY Ardsley
- 专利权人： Acorda Therapeutics, Inc.
- 当前专利权人： Acorda Therapeutics, Inc.
- 当前专利权人地址： US NY Ardsley
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K47/54
- IPC分类号： A61K47/54 ; A61K31/661 ; C07F9/09 ; C07C233/25 ; C07F9/11
摘要：
The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
公开/授权文献
- US20180086778A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME 公开/授权日：2018-03-29
信息查询
