Methods are provided for detection of a disease breakout from a mammal population. For example, the method involves continuously receiving, from two or more sensors positioned in a mammal environment, information of a population of mammals, wherein the information received from each of the two or more sensors is in a different data format; comparing the received information of the population of mammals or other animals with known disease symptom information; and in response to determining that the information of the population of mammals exceeds a pre-determined threshold alert level, generating an alert to prevent or control the disease; wherein the steps of the method are performed in accordance with a processor and a memory.