Techniques for channelization of a wireless communication network in the presence of interference are described. In one embodiment, a method includes detecting an unlicensed wireless wide area network signal. The method includes selecting a wireless channel for a wireless local area network that includes frequencies associated with the unlicensed signal. The method includes allocating a first portion of the wireless channel that includes frequencies associated with the unlicensed signal to a first plurality of resource units and allocating a second portion of the wireless channel that excludes frequencies associated with the unlicensed signal to a second plurality of resource units. The method includes assigning the first plurality of resource units to a first group of client devices, and assigning the second plurality of resource units to a second group of client devices.