- 专利标题: Methods for generating barcoded combinatorial libraries
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申请号: US15948798申请日: 2018-04-09
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公开(公告)号: US10287575B2公开(公告)日: 2019-05-14
- 发明人: Ryan T. Gill , Andrew Garst , Tanya Elizabeth Warnecke Lipscomb , Marcelo Colika Bassalo , Ramsey Ibrahim Zeitoun
- 申请人: The Regents of the University of Colorado , Inscripta, Inc.
- 申请人地址: US CO Denver US CO Boulder
- 专利权人: The Regents of the University of Colorado, a body corporate,Inscripta, Inc.
- 当前专利权人: The Regents of the University of Colorado, a body corporate,Inscripta, Inc.
- 当前专利权人地址: US CO Denver US CO Boulder
- 代理机构: Wilson Sonsini Goodrich & Rosati
- 主分类号: C12N15/10
- IPC分类号: C12N15/10 ; C12N15/11
摘要:
Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases.
公开/授权文献
- US20180230461A1 METHODS FOR GENERATING BARCODED COMBINATORIAL LIBRARIES 公开/授权日:2018-08-16
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