- 专利标题: Pegylated OXM variants
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申请号: US14725883申请日: 2015-05-29
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公开(公告)号: US10166295B2公开(公告)日: 2019-01-01
- 发明人: Udi Eyal Fima , Oren Hershkovitz
- 申请人: Opko Biologics Ltd.
- 申请人地址: IL Kiryat Gat
- 专利权人: OPKO Biologics Ltd.
- 当前专利权人: OPKO Biologics Ltd.
- 当前专利权人地址: IL Kiryat Gat
- 代理机构: Pearl Cohen Zedek Latzer Baratz LLP
- 代理商 Mark S. Cohen
- 主分类号: A61K38/26
- IPC分类号: A61K38/26 ; A61K47/48 ; A61K38/22
摘要:
A composition which includes oxyntomodulin and polyethylene glycol polymer (PEG polymer) linked via a reversible linker such as 9-fluorenylmethoxycarbonyl (Fmoc) or sulfo-9-fluorenylmethoxycarbonyl (FMS) is disclosed. Pharmaceutical compositions comprising the reverse pegylated oxyntomodulin and methods of using same are also disclosed.
公开/授权文献
- US20150258208A1 PEGYLATED OXM VARIANTS 公开/授权日:2015-09-17
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