A spacer profile adapted to be used in a spacer frame of an insulating glass unit includes a hollow profile body made of a first synthetic material and a chamber for accommodating hydroscopic material, the hollow profile body having an inner wall that is, in an assembled state of the insulating glass unit, directed to the intervening space between panes of the insulating glass unit, an outer wall on the opposite side of the inner wall, a first side wall and a second side wall on the opposite side to the first side wall, the walls being connected to form the chamber, and a diffusion barrier portion made of a second synthetic material with sheet silicates and being formed as at least a part of the outer wall.