A method for reducing image disturbances caused by reconstructed defective pixel clusters located in signal-gradient affected diagnostic image regions. An individually adapted central symmetrical pair reconstruction (CSP) kernel is composed for a defective image pixel based on a kernel-pair candidate order encoded in a model thereby using the pixel's validity state. The image impacted by defective pixels is corrected in real-time by statistical filtering or spatial convolution of the kernel-associated image data accessible via a predetermined CSP kernels image-offsets structure.