Disclosed aspects relate to generating rationales for treatment options. A set of preference scores that indicates a first preference score for a first treatment option of a set of treatment options may be received. A rank-order that indicates a first ranking for the first treatment option may be received. The set of preference scores may be analyzed with respect to the rank-order to determine a relationship between the first preference score and the first ranking for the first treatment option. Based on the relationship between the first preference score and the first ranking, a set of rationale data for the first treatment option may be generated with respect to the first rank. Based on a user profile for a user, the set of rationale data may be configured for the user. The set of rationale data which is configured for the user may be provided.