A tire for a two-wheeled motor vehicle has a tread (2) including: a center region (Cr); a pair of middle regions (Mr) located on both sides of the center region (Cr); and a pair of inner shoulder regions (Sr) located on both sides of the middle regions (Mr). The tread (2) has provided therein: inner tilted grooves (10) having outer ends (10e) provided within the middle regions (Mr); and outer tilted grooves (11) having inner ends (11i) provided within the middle regions (Mr). The groove area ratio of the center region (Cr) is from 34% to 39%, the groove area ratio of the middle regions (Mr) is from 14% to 19%, and the groove area ratio of the inner shoulder regions (Sr) is from 14% to 19%.