The utility model relating to the highly effective waterproof honeycomb clad plate comprises a honeycomb core, and a panel which is composite on four lateral faces of the clad plate. The utility model is characterized in that the panel is composite construction, whose outer layer is paper, and the inner layer is plastic. The panel of the utility model is paper-plastic-paper multilayered structure, the adhesion of the glue is not affected for the inner, and the print and wear preventive are not affected for the outer. In particular, the utility model is suitable for not only the tray-manufacturing but the producing, manufacturing and using in the high wet areas. All the four lateral faces embedding with the panels block the whole honeycomb core, and prevent the permeation of the damp air and the penetration after the dripping efficiently.