The utility model relates to an anti-sliding infusion sleeve which comprises an arm pad. Wherein the arm pad is rectangular, a palm pad is sewed at the head part of the arm pad, a hand back fixing band and an elbow fixing band are respectively sewed at the left side of the arm pad body, and a thorn hair layer fixedly connected with the tail ends of the hand back fixing band and the elbow fixing band is matched with a round hair layer fixedly connected with the back surface of the arm pad in a sticking manner. The arm pad is designed from the perspective of breathability and comfort, the hard plate inserted into the arm pad can be used for stretching the arms of a patient, and the soft arm pad enables the patient to enjoy comfortable touch feeling. The autonomously-adjusted hand back fixingband and elbow fixing band can be suitable for patients of all ages to use.