The utility model provides a packaging hardware of powder medicine, send a bag mechanism, opening bag mechanism and sealing mechanism including what set gradually, send two conveyer belts of bag mechanism including setting up side by side, opening bag mechanism includes that the bottom plate has offered a spout on the bottom plate, and it is provided with two sliders to slide in the spout, and each fixedly being provided with a support on two sliders, respectively is provided with a vacuum chuck on two supports, all set up the just screw thread reversion of two screws of a screw on two sliders, two sliders pass through the screw cover to be established on a lead screw, and the one end of lead screw is connected with a motor, the lead screw divide into the three -section, is plus thread section, smooth changeover portion and left -hand thread section in proper order, and two sliders overlap respectively to be established in plus thread section and left -hand thread section, bag roller is vice, hot melt sealing device and go out that the bag roller is vice to be constituteed by connecing of setting gradually for sealing mechanism. The utility model provides a packaging hardware of powder medicine can realize sending the bag, open bag, powder charge and confined process, simple structure moreover.