The utility model belongs to the field of medical intervention consumables, and particularly relates to a gradient-thickness coronary stent suitable for coronary artery tortuosity angulation, in particular for an angiosteosis-accompanying lesion. The stent consists of a plurality of enclosed wave-shaped annular units, wherein each annular unit is connected along the axial direction of a guide wire moving direction through connecting pieces; the stent is partitioned into a head end and a tail end along a guide wire advancing direction; under the situation that the inner diameter of each annular unit is kept consistent, the outer diameter of the stent in an expansion state increases gradually from a vertex position at the head end of the stent to the vertex position at the tail end of the stent, thereby forming a circular stent structure. On the premise that the stent is as thin as possible, the other characteristics of radial strength, fatigue resistance, trackability, propelling movement, transparency, elastic return and the like can be kept. The gradient-thickness coronary stent is suitable for intervention treatment of coronary artery tortuosity angulation, in particular for the angiosteosis-accompanying lesion.