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实用新型
CN204182007U 一种超声控释药物洗脱球囊导管 失效 - 权利终止

一种超声控释药物洗脱球囊导管
摘要：
本新型公开了一种超声控释药物洗脱球囊导管。该导管包括普通球囊导管、球囊表面亲水涂层、超声响应微囊及微囊中包裹的药物组成。药物被包裹于微囊中。使用时，将药物洗脱球囊导管送达病变部位后撑开、球囊与病变组织接触，体外对病变部位施以超声诱导，在超声作用下，加速载药微囊脱离亲水性粘合剂，向具有脂溶性的病变组织中扩散，同时具有超声响应特性的载药微囊在超声作用下发生破裂、释放药物，药物被靶病变组织吸收利用的效率将得到大幅度提高。通过调整载药微囊特性、超声特性，可实现对药物释放量、释放时间的控制，提高药物洗脱球囊导管的有效性和安全性。
摘要（英）：

The utility model discloses a drug eluting balloon catheter by ultrasonic controlled release. The catheter is composed of an ordinary balloon catheter, a hydrophilic coating of a balloon surface, ultrasonic responsive micro capsules and medicine wrapped into the micro capsules. During operation, the drug eluting balloon catheter is conveyed to a diseased position and then dilated, and balloons are in contact with diseased tissue. Ultrasonic induction is applied to the diseased position in vitro. Under ultrasonication, the micro capsules carrying medicine can be separated from a hydrophilic adhesive acceleratedly and diffuse to fat-soluble diseased tissue. Under ultrasonication, the micro capsules carrying medicine provided with characteristics of ultrasonic response break to release medicine such that absorption and utilization efficiency of medicine by target lesion tissue can be significantly enhanced. By adjusting characteristics of micro capsules carrying medicine and ultrasonication, control over release of medicine amount and release time can be achieved in order to improve effectiveness and safety of the drug eluting balloon catheter.

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