The utility model discloses a flue-cured tobacco leaf clamping operation machine which mainly comprises a frame body, a pedal transmission device and a handle transmission device. The frame body is provided with a work table. The two sides of the work table are respectively provided with one baffle shaped like a Chinese character 'shan'. The two sides of the frame body are respectively provided with one supporting frame. The supporting frames are located in notches of the baffles. The lower side of the frame body is provided with the pedal transmission device and the handle transmission device. The lower ends of the supporting frames are connected with the pedal transmission device in a transmission mode. The middle sections of the supporting frames are connected with the handle transmission device in a transmission mode. By the adoption of the structure, the clamping efficiency of tobacco leaves is improved, the clamping density of the tobacco leaves is increased, and the semi-automatic working process is achieved.