The utility model discloses a charge-coupled device camera and light source adjusting and combining structure used for the intelligent detection of printed matter. The structure comprises guide track grooves at two sides, two fixed bases which are distributed symmetrically, two long cross-shaped guide fixed supporting chute rods which are distributed in a linear way, three camera hanging and fixing frames which are arrayed in a linear way and two light sources which are fixed, form a certain angle and are arranged symmetrically. The structure can improve the imaging quality of images and the quality of edge extraction and acquisition and processing of back end images. In addition, the cost of equipment is greatly reduced, collected images are ensured to be acquired, the precision is improved and the error is reduced. On the basis of meeting the requirement of speed, the stability is ensured to be good, the dynamic error is small and the optimal collected image effect is acquired. In addition, the structure has characteristics of simplicity in structure, low manufacturing cost, simplicity in installation and convenience in assembly and disassembly.