The utility model discloses a cyclone dust removal device of cut tobacco moisture regain equipment. A discharge end of a cut tobacco moisture regain rotary drum of the cut tobacco moisture regain equipment is provided with a discharge cover, a discharge shaking groove is arranged under the bottom end of the discharge groove, a dust removal pipeline at the top end of the discharge cover is connected with a cyclone dust extractor, and a dust removal cylinder used to receive dust is arranged below the cyclone dust extractor. According to the cyclone dust removal device of the cut tobacco moisture regain equipment, the cut tobacco moisture regain rotary drum is additionally provided with the cyclone dust extractor, and the cyclone dust removal device of the cut tobacco moisture regain equipment has the advantages of being simple to install, good in dust removal effect, low in cost, and free of jamming of the centralized dust removal pipeline. An original dust removal screen is detached, after dust and steam pass the cyclone dust extractor, the dust automatically falls into the dust removal cylinder, and therefore the phenomenon that the dust absorbed on the outer surface of the screen absorbs the environment steam, becomes small damp ball-shaped cut tobacco and falls on finished cut tobacco to cause quality risks due to the jamming of the dust removal screen is avoided.