The utility model relates to a double-shaft self-cleaning reactor which comprises a set of cylinder body and two rotors, wherein two feed openings, discharge openings and exhaust openings are formed on the cylinder body, and a jacket/ pipe coil used for cooling/heating is further arranged on the cylinder body. The two rotors are positioned inside the cylinder body, and a plurality of sets of meshed plates and stirring plates are arranged on the rotors. The double-shaft self-cleaning reactor provided by the utility model has the advantages of strong stirring capability, strong self-cleaning capability and large heat exchange area, can achieve continuous production, is narrow in reactant residence time distribution, can achieve laminar flow of reactant, and is suitable for polyreaction and devolatilization reaction of various polymer materials.