The utility model discloses a stirring device for high dissolved oxygen fermentation, which comprises a stirring shaft and stirring paddles arranged on the stirring shaft. The stirring paddles include a press push type paddle arranged at the upper portion of the stirring shaft and at least one layer of broken bubble paddles arranged below the press push type paddle. By means of changes of the stirring paddles, the stirring device for the high dissolved oxygen fermentation resolves the problem that the volume of dissolved oxygen is not sufficient in a fermentation tank, reduces fermentation reaction time, and greatly improves reaction rate.