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发明授权
CN1986001B 生物护创膜 有权 转让

生物护创膜
摘要：
本发明公开了一种生物型护创膜及其制备方法，它由经非醛类固定剂交联固定和去抗原处理过的动物肠膜为基材(1)而构成，在所述基材(1)的表面上设了含有可粘附细胞的纤连蛋白、层粘连蛋白或玻连蛋白的活性修饰层(2)，或含有抗菌药的抗菌缓释层(2)。本发明的优点是：它是用很薄而坚韧的动物肠膜制成，质量轻而柔软，使用方便。肠膜属于半透膜，微孔小而密，透气及透汽性好，但不透过细菌，又经多方位除抗原处理，有效去除免疫抗原性，再加上表面活性修饰，可征集上皮细胞及成纤维细胞，促进创面愈合；或能缓释抗菌药，增大抗感染作用，其使用性能及护创效果比猪皮制成的敷料或保护膜好。
摘要（英）：

The present invention discloses a kind of biological wound-protecting film and its preparation process. The biological wound-protecting film consists of animal intestine membrane through cross-linking and fixing with non-aldehyde fixing agent and antigen-eliminating treatment as the base material (1), and surface active modifying layer of fibronectin, laminin or vitronectin capable of adhering cell or antiseptic slow releasing layer (2) with antiseptic. The present invention has the advantages of light weight, softness, high air permeation, bacterial impermeability, effectively elimination of immunogenicity, surface active modification, capacity of promoting wound healing, increased antiinflammation and excellent use performance and wound protecting effect.

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