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发明授权
CN1947740B 独一味药材、中间体及其注射液的指纹图谱检测方法 失效 - 权利终止 转让

独一味药材、中间体及其注射液的指纹图谱检测方法
摘要：
本发明公开独一味药材、中间体及其注射液的指纹图谱质量检测方法。该方法色谱条件及系统适用性试验：用十八烷基硅烷键合硅胶为填充剂，进行梯度洗脱；取槲皮素对照品，加甲醇制成40μg/ml的溶液，作为参照物溶液；独一味药材供试品溶液的制备：取药材粉末，回流提取，滤过，水液蒸干，残渣加甲醇适量溶解，离心；上清液，加参照物溶液，甲醇定容，摇匀，滤过，取滤液，即得；中间体及其注射液供试品溶液的制备：取独一味注射液中间体或注射液，加参照物溶液，甲醇稀释，摇匀，滤过，取滤液，即得；测定法：吸取参照物溶液和供试品溶液，注入液相色谱仪中，测定；供试品指纹图谱与对照指纹图谱相似度大于0.90。
摘要（英）：

A fingerprint method for testing the quality of common lamiophlomis, its intermediate and its injection includes such steps as preparing the reference solution from quercetin, preparing three solutions of common lamiophlomis, its intermediate and its injection, filling the reference solution and one solution to be tested into liquid-phase chromatograph, and testing the similarity between their fingerprints, which must be greater than 0.90.

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