The invention is a micro-optical combination device applied to a body surface, which includes a packaging component, a luminous component, a sensing component, an optical guide component and a lens; wherein, the packaging component includes a first separating room and a second one, the first one set with a first hole and the second one with a second hole; wherein, the luminous component fixed in the first separating room and the optical guide component in the first hole; and the sensing component fixed in the second separating room and the lens in the second hole. The light can be emitted by the first hole, and after reflected by the body surface, received through the second hole.