The present invention relates to a Chinese medicine Liufukang oral liquor matched with chemotherapy for curing late tumor and its preparation method. It is made from 14 Chinese medicinal materials ofiron holly bark, hedyotis, bearded scutellaria, American ginseng, astragalus root, ovate atractylodes root, pinellia tuber and others through the processes of boiling by adding water to extract, filtering, heating, concentrating, regulating concentration, fine-filtering, filling, sealing and sterilizing to obtain the finished product. Said oral liquor possesses the functions of enriching supplementation and resisting cancer, increasing white blood cell, wheting appetite, obviously reducing toxic side effect of radiotherapy and chemotherapy and raising therapeutic effect.