The invention discloses a portable intelligent self-service terminal based on 5G communication real-time interaction. The portable intelligent self-service terminal comprises a host provided with a main control core board, wherein the main control core board is provided with a WIFI/Bluetooth module, a GPS module, a hard disk and a memory bank; the host serves as a control and data processing coreof the self-service terminal and is connected to an operation screen, a sensor IO module, an auxiliary all-in-one machine, a biological recognition module, a 5G communication module, a power management module, a card reading/card issuing module, a password keyboard and a standby expansion module through a host interface. The instant information interaction function, the signal portability, the cloud computing function and the AI function of the self-service terminal are achieved based on 5G communication, the Internet of things technology is popularized into the self-service terminal, and dueto the characteristics of low time delay and high speed of the 5G communication module, the self-service terminal is portable, and meanwhile the powerful cloud computer mass data interaction capacityis achieved.