The embodiment of the invention discloses an asynchronous first-in first-out data processing method, which is applied to the technical field of storage and comprises the following steps of confirmingwhether a current binary pointer of a source clock domain is greater than the depth for realizing asynchronous first-in first-out or not; if yes, adding a preset depth difference value to the currentbinary pointer to obtain a first temporary binary pointer, converting the first temporary binary pointer into a Gray code pointer, and sending the Gray code pointer to an opposite end clock domain; converting the Gray code pointer into a second temporary binary pointer by the opposite end clock domain, and determining whether the second temporary binary pointer is greater than the depth for realizing asynchronous first-in first-out or not; and if so, subtracting the preset depth difference value from the second temporary binary pointer to obtain a target binary pointer. The embodiment of the invention further discloses an asynchronous first-in first-out data processing device, an electronic device and a computer readable storage medium, asynchronous FIFO at any depth can be achieved, and storage chip resources are saved.