The invention belongs to the technical field of release agents, and relates to an organic-silicone-based release agent, in particular to an organic silicone release agent for an artificial board and apreparation method of the organic silicon release agent. The organic silicon release agent is prepared from the compositions in percentage by mass: 4-8% of organic silicone resin, 2-6% of methyl silicone oil, 0.2-1% of an accelerator, 0.2-1% of a masking agent, and the balance isopropyl alcohol, wherein the isopropyl alcohol is a solvent; the organic silicone resin is any one or more of methyltrichlorosilane, dimethyldichlorosilane, phenyltrichlorosilane, and diphenyldichlorosilane; the accelerator is any one of tetrabutyl titanate, dibutyltin dilaurate, bismuth laurate and stannous isooctanoate; and the masking agent is any one or more of N,N-Dimethylisopropanolamine, ethylenediamine, triethylamine, triethylenediamine. The organic silicone release agent is liquid at room temperature, andhas the advantages of small surface tension, low stress during release, good release durability, high temperature resistance, non-toxicity, low cost, good glossness after releasing and non-mold-contaminating.