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发明公开
CN110551813A 用于检测风湿免疫疾病的药物代谢能力的相关SNP位点的引物组、应用、产品及方法 有权

用于检测风湿免疫疾病的药物代谢能力的相关SNP位点的引物组、应用、产品及方法
摘要：
本发明提供了一种用于检测风湿免疫疾病的药物代谢能力的相关SNP位点的引物组、应用、产品及方法，涉及生物技术领域，本发明提供的用于检测风湿免疫疾病的药物代谢能力的相关SNP位点的引物组，能够用于检测免疫抑制剂代谢能力、免疫调节剂代谢能力、抗炎药代谢能力、TNF抑制剂代谢能力、B细胞调节剂代谢能力、IL-6抑制剂代谢能力、降尿酸剂代谢能力和排尿酸药代谢能力，该引物组针对风湿免疫疾病常见药物代谢相关的主要突变位点进行设计，可以对风湿免疫疾病常见药物代谢相关的位点突变实现特异性检测，准确性高，能够极大的缩短检测周期，同时降低检测成本。
摘要（英）：

The invention provides a primer group, an application, a product and a method for detecting SNP (single nucleotide polymorphism) loci related to drug metabolism capacity of rheumatic immunological diseases, and relates to the technical field of biology. The primer group for detecting the SNP loci related to the drug metabolism capacity of the rheumatic immunological diseases can be used for detecting metabolism capacity of an immunosuppressor, metabolism capacity of an immunomodulator, metabolism capacity of an anti-inflammatory agent, metabolism capacity of a TNF inhibitor, metabolism capacity of a B cell regulator, metabolism capacity of an IL-6 inhibitor, metabolism capacity of a uric acid lowering agent and metabolism capacity of a uricosuric agent. The primer group is designed for main mutation sites related to common drug metabolism of the rheumatic immunological diseases, can realize specific detection for locus mutation related to common drug metabolism of the rheumatic immunological diseases, and can greatly shorten detection cycle and reduce detection cost.

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