The invention discloses an intelligent magneto-rheological vibration reduction pipe clamp. A pipe clamp upper shell and a pipe clamp lower shell are matched to form a cavity, an inner pipe clamp is positioned in the cavity, and the cavity is also provided with an inlet and an outlet through which a pipeline enters and exits. The intelligent magneto-rheological vibration reduction pipe clamp further comprises a magneto-rheological damper, a displacement sensor used for detecting the pipeline displacement information and a controller used for calculating the working current of the magneto-rheological damper. The inner pipe clamp is connected with the pipe clamp upper shell and/or the pipe clamp lower shell through the magneto-rheological damper, the displacement sensor and the controller arefixed on the pipe clamp upper shell and/or the pipe clamp lower shell, the displacement sensor is in signal connection with the controller, and the controller is in signal connection with the magneto-rheological damper. According to the present invention, the high integration of a magneto-rheological technology, an embedded control system and the pipe clamp can be achieved, the pipe clamp has theadvantages of being continuously adjustable in damping force, high in response speed, high in reliability, low in energy consumption, wide in adaptability and the like, and the pipe clamp can still serve as the passive control equipment to work under the condition that no external energy is supplied.