The invention discloses a treatment method of worm egg shells in a cashmere fabric. The method comprises the steps of pre-washing, preparation of an enzyme treatment solution, an enzyme treatment reaction, steaming, washing, drying and the like. According to the treatment method of the worm egg shells in the cashmere fabric, scale layers of cashmere fibers and the worm egg shells are simultaneously hydrolyzed by a compound enzyme composed of cutinase, protease and glucoside hydrolase. Steaming helps to increase the breakage probability of the worm egg shells, the treated cashmere fabric is softer in hand feeling, and the local color depth caused by the worm egg shells is improved.