The invention discloses a distributed multi-party random number generation method and system based on hardware. The distributed multi-party random number generation method comprises the following steps: dividing a time slice into a plurality of periods, and sorting at least two random number generation nodes in a current period; enabling the first random number generation node in the current period to select a true random number and broadcast the true random number to other random number generation nodes; and enabling the current random number generation node to receive the true random numberbroadcasted by the previous random number generation node, verify the true random number, combine and sign the true random number generated by the current random number generation node and the true random number broadcasted by the previous random number generation node after the verification is passed, and broadcast the signed true random number to other random number generation nodes. According to the invention, a mechanism of formulating a protocol among multiple parties is adopted to combine random numbers generated by a plurality of nodes to generate a final random number, which does not depend on a specific hardware chip, so that a malicious party can be prevented from falsifying the random number privately.