The invention discloses an informatization platform monitoring system and a construction method, and belongs to the field of micro-service architecture monitoring management design. The construction method of an informatization platform monitoring system comprises the following steps of establishing a micro-service architecture among subsystems by utilizing spring cloud; monitoring the operation health state of each subsystem, collecting the interface name of each subsystem when monitoring that each subsystem operates healthily, setting the access permission and frequency of the interface of each subsystem, and managing the interface data of each subsystem. An informatization platform monitoring system comprises a deployment module, a monitoring module and an interface use management module. According to the method and the system, the access permission and times of the interface are customized according to the requirements of the system, and the access permission and times of the interface of each subsystem are effectively managed, so that the potential safety hazard that the interface is illegally and maliciously accessed is effectively reduced.