The invention provides a 220 kV outdoor power transformation equipment grounding wire clamp based on an unmanned aerial vehicle technology. The 220 kV outdoor power transformation equipment groundingwire clamp comprises a concave shell, an unmanned aerial vehicle, a remote control device and a first spring; the concave shell is provided with an unmanned aerial vehicle connector used for being connected with the unmanned aerial vehicle; the concave shell is connected with a grounding wire; the concave shell comprises a first occlusion wall and a lower wall which are arranged at the interval ofa distance, and a side wall with two ends connected with one end of the first occlusion wall and one end of the lower wall respectively; semicircular concave parts are arranged on the first occlusionwall and a second occlusion wall; the second occlusion wall slides upwards in a height direction of the side wall and is occluded with the first occlusion wall; the semicircular concave parts are abutted against each other to form a circular clamping hole; and the circular clamping hole is used for clamping a conductor and is electrically connected with the conductor. By applying the technical scheme, a safer operation environment in which operation personnel do not need to be in direct contact with high-voltage electricity can be realized.