The invention provides automatic welding equipment for a guide wire; the automatic welding equipment for the guide wire comprises a a machine frame, a conveying device, a limiting and fixing device, astretching device, a cutting device, a welding device, a material box, and a control device, wherein the conveying device is arranged on the machine frame for conveying an inner core, a spring and afinished guide wire; the limiting and fixing device is arranged on the machine frame for limiting the spring radially when the spring reaches a welding station and fixing the spring when the end of the spring reaches a welding point; the stretching device is arranged on the machine frame for stretching the two ends of the spring and the two ends of the inner core to the welding point; the cuttingdevice is arranged on the machine frame for cutting the inner core and the spring; the welding device is arranged on the machine frame for welding the two ends of the spring and the two ends of the inner core respectively; the material box is arranged at an output end of the conveying device to receive the finished product guide wire conveyed by the conveying device; and the control device is arranged on the machine frame and electrically and respectively connected with the conveying device, the limiting and fixing device, the stretching device, the cutting device and the welding device. The automatic welding equipment for the guide wire provided by the invention improves the welding efficiency of the guide wire and reduces the production cost of the guide wire.