The invention relates to a safe and stable control main station information interaction method suitable for a large-scale power grid. A safe and stable control system comprises a plurality of main stations and a plurality of execution stations. The method is applied to any one main station in the safe and stable control system. The method comprises the steps of receiving state information and datainformation sent by all the execution stations in the safe and stable control system, and generating first execution station information according to the state information and the data information; acquiring first execution station information of other main stations in the safe and stable control system; and correcting abnormal data of the local first execution station information according to the first execution station information of other main stations to obtain second execution station information. The actions of all the main stations can be effectively ensured to be consistent, so that the occurrence of bad conditions such as relatively wide-range over-cutting and the like is effectively avoided.